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''Yersinia pseudotuberculosis'' is a Gram-negative bacterium that causes Far East scarlet-like fever in humans, who occasionally get infected zoonotically, most often through the food-borne route. Animals are also infected by ''Y. pseudotuberculosis''. The bacterium is urease positive. ==Pathogenesis== In animals, ''Y. pseudotuberculosis'' can cause tuberculosis-like symptoms, including localized tissue necrosis and granulomas in the spleen, liver, and lymph nodes. In humans, symptoms of Far East scarlet-like fever are similar to those of infection with ''Yersinia enterocolitica'' (fever and right-sided abdominal pain), except that the diarrheal component is often absent, which sometimes makes the resulting condition difficult to diagnose. ''Y. pseudotuberculosis'' infections can mimic appendicitis, especially in children and younger adults, and, in rare cases, the disease may cause skin complaints (erythema nodosum), joint stiffness and pain (reactive arthritis), or spread of bacteria to the blood (bacteremia). Far East scarlet-like fever usually becomes apparent five to 10 days after exposure and typically lasts one to three weeks without treatment. In complex cases or those involving immunocompromised patients, antibiotics may be necessary for resolution; ampicillin, aminoglycosides, tetracycline, chloramphenicol, or a cephalosporin may all be effective. The recently described syndrome "Izumi-fever" has been linked to infection with ''Y. pseudotuberculosis''. The symptoms of fever and abdominal pain mimicking appendicitis (actually from mesenteric lymphadenitis) associated with ''Y. pseudotuberculosis'' infection are not typical of the diarrhea and vomiting from classical food poisoning incidents. Although ''Y. pseudotuberculosis'' is usually only able to colonize hosts by peripheral routes and cause serious disease in immunocompromised individuals, if this bacterium gains access to the blood stream, it has an LD50 comparable to ''Y. pestis'' at only 10 CFU. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Yersinia pseudotuberculosis」の詳細全文を読む スポンサード リンク
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